tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate

97%

  • Product Code: 128213
  CAS:    617714-22-4
Molecular Weight: 225.28 g./mol Molecular Formula: C₁₂H₁₉NO₃
EC Number: MDL Number: MFCD17016701
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry
Product Description: Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿5,220.00
+
-
250mg 10-20 days ฿9,300.00
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-
500mg 10-20 days ฿16,070.00
+
-
tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.
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