tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
97%
- Product Code: 128213
CAS:
617714-22-4
Molecular Weight: | 225.28 g./mol | Molecular Formula: | C₁₂H₁₉NO₃ |
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EC Number: | MDL Number: | MFCD17016701 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | ฿5,220.00 |
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250mg | 10-20 days | ฿9,300.00 |
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500mg | 10-20 days | ฿16,070.00 |
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tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.
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