Trimethyl(trifluoromethyl)silane
2 M in THF
- Product Code: 128348
CAS:
81290-20-2
| Molecular Weight: | 142.19 g./mol | Molecular Formula: | C₄H₉F₃Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00145454 | |
| Melting Point: | Boiling Point: | 54-55 °C(lit.) | |
| Density: | 0.962 g/mL at 20 °C(lit.) | Storage Condition: | 2-8°C |
Product Description:
Used as a reagent in organic synthesis, particularly for introducing trifluoromethyl groups into molecules. This transformation is valuable in pharmaceutical and agrochemical industries, where trifluoromethylation enhances metabolic stability, lipophilicity, and bioavailability of active compounds. It serves as a source of nucleophilic trifluoromethyl anions when activated by fluoride ions, enabling reactions with electrophilic substrates such as aldehydes, ketones, and imines. Commonly applied in the preparation of trifluoromethylated alcohols and amines, which are key structural motifs in drug development. Its use in modern fluorination chemistry makes it a tool of choice for late-stage functionalization in complex molecule synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 10ml | 10-20 days | ฿3,190.00 |
+
-
|
Trimethyl(trifluoromethyl)silane
Used as a reagent in organic synthesis, particularly for introducing trifluoromethyl groups into molecules. This transformation is valuable in pharmaceutical and agrochemical industries, where trifluoromethylation enhances metabolic stability, lipophilicity, and bioavailability of active compounds. It serves as a source of nucleophilic trifluoromethyl anions when activated by fluoride ions, enabling reactions with electrophilic substrates such as aldehydes, ketones, and imines. Commonly applied in the preparation of trifluoromethylated alcohols and amines, which are key structural motifs in drug development. Its use in modern fluorination chemistry makes it a tool of choice for late-stage functionalization in complex molecule synthesis.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :