Diethyl (1-oxo-1-phenylpropan-2-yl)phosphonate
96%
- Product Code: 129461
CAS:
10409-56-0
| Molecular Weight: | 270.26 g./mol | Molecular Formula: | C₁₃H₁₉O₄P |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 156.5-158 °C at 1.5 mmHg | |
| Density: | 1.1328 g/cm3 | Storage Condition: | Room temperature, seal, inert gas |
Product Description:
Used as a key intermediate in the synthesis of α,β-unsaturated carbonyl compounds through the Horner-Wadsworth-Emmons (HWE) olefination reaction. It enables the selective formation of trans-configured enones when reacted with aldehydes under basic conditions. Its phosphonate group stabilizes the carbanion, facilitating carbon-carbon bond formation in pharmaceutical and fine chemical manufacturing. Particularly valuable in constructing conjugated systems found in bioactive molecules and natural product analogs. Shows good reactivity with aromatic and aliphatic aldehydes, making it versatile in organic synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿3,760.00 |
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| 250mg | 10-20 days | ฿6,180.00 |
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| 1g | 10-20 days | ฿21,370.00 |
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Diethyl (1-oxo-1-phenylpropan-2-yl)phosphonate
Used as a key intermediate in the synthesis of α,β-unsaturated carbonyl compounds through the Horner-Wadsworth-Emmons (HWE) olefination reaction. It enables the selective formation of trans-configured enones when reacted with aldehydes under basic conditions. Its phosphonate group stabilizes the carbanion, facilitating carbon-carbon bond formation in pharmaceutical and fine chemical manufacturing. Particularly valuable in constructing conjugated systems found in bioactive molecules and natural product analogs. Shows good reactivity with aromatic and aliphatic aldehydes, making it versatile in organic synthesis.
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