(5-bromopyridin-3-yl) tert-butyl carbonate

95%

  • Product Code: 129475
  CAS:    1087659-21-9
Molecular Weight: 274.1 g./mol Molecular Formula: C₁₀H₁₂BrNO₃
EC Number: MDL Number:
Melting Point: Boiling Point: 319.8±42.0 °C(Predicted)
Density: 1.424±0.06 g/cm3(Predicted) Storage Condition: Room temperature, seal, dry
Product Description: Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other biologically active compounds. The bromine substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the construction of complex heterocyclic systems. The tert-butyloxycarbonyl (Boc) protecting group stabilizes the nitrogen during synthetic transformations and can be easily removed under mild acidic conditions when needed. Its structure makes it valuable in medicinal chemistry for optimizing lead compounds and improving selectivity or potency in drug candidates targeting neurological disorders, inflammation, and cancer.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿8,790.00
+
-
250mg 10-20 days ฿15,390.00
+
-
1g 10-20 days ฿43,990.00
+
-
(5-bromopyridin-3-yl) tert-butyl carbonate
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other biologically active compounds. The bromine substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the construction of complex heterocyclic systems. The tert-butyloxycarbonyl (Boc) protecting group stabilizes the nitrogen during synthetic transformations and can be easily removed under mild acidic conditions when needed. Its structure makes it valuable in medicinal chemistry for optimizing lead compounds and improving selectivity or potency in drug candidates targeting neurological disorders, inflammation, and cancer.
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