2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine
95%
- Product Code: 129802
CAS:
2792143-50-9
| Molecular Weight: | 307.5 g./mol | Molecular Formula: | C₁₂H₁₄BClF₃NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD13182153 | |
| Melting Point: | Boiling Point: | 344.3±42.0 °C(Predicted) | |
| Density: | 1.27±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to synthesize pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of trifluoromethyl-substituted pyridine derivatives, which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, inflammation, and metabolic diseases. Also employed in the preparation of advanced intermediates for crop protection agents due to the stability and lipophilicity imparted by the trifluoromethyl group.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $135.61 |
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| 250mg | 10-20 days | $236.65 |
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2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to synthesize pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of trifluoromethyl-substituted pyridine derivatives, which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, inflammation, and metabolic diseases. Also employed in the preparation of advanced intermediates for crop protection agents due to the stability and lipophilicity imparted by the trifluoromethyl group.
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