4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
97%
- Product Code: 129834
CAS:
2357117-23-6
| Molecular Weight: | 573.04 g./mol | Molecular Formula: | C₂₅H₃₇ClN₄O₉ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32903279 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of antibody-drug conjugates (ADCs), particularly in linking cytotoxic agents to monoclonal antibodies. Its structure contains a primary amine group that enables stable conjugation to activated carboxyl groups on antibodies or other biomolecules. The polyether chain provides water solubility and flexibility, improving the pharmacokinetic profile of the resulting conjugate. The isoindoline dione moiety with a dioxopiperidyl group contributes to target binding properties, often associated with cereblon modulation, making it valuable in targeted cancer therapies. Commonly applied in the development of precision oncology drugs where selective delivery of potent cytotoxins to tumor cells is required.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿6,390.00 |
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| 0.100 | 10-20 days | ฿11,840.00 |
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| 0.250 | 10-20 days | ฿23,660.00 |
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4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Used as a key intermediate in the synthesis of antibody-drug conjugates (ADCs), particularly in linking cytotoxic agents to monoclonal antibodies. Its structure contains a primary amine group that enables stable conjugation to activated carboxyl groups on antibodies or other biomolecules. The polyether chain provides water solubility and flexibility, improving the pharmacokinetic profile of the resulting conjugate. The isoindoline dione moiety with a dioxopiperidyl group contributes to target binding properties, often associated with cereblon modulation, making it valuable in targeted cancer therapies. Commonly applied in the development of precision oncology drugs where selective delivery of potent cytotoxins to tumor cells is required.
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