4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoic acid
98%
- Product Code: 129864
CAS:
2121513-72-0
| Molecular Weight: | 316.08 g./mol | Molecular Formula: | C₁₄H₁₆BF₃O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28356850 | |
| Melting Point: | Boiling Point: | 382.2±42.0 °C(Predicted) | |
| Density: | 1.27±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester precursor in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its trifluoromethyl and carboxylic acid functional groups enable selective transformations and facilitate the construction of biaryl structures with enhanced metabolic stability and lipophilicity. The presence of the dioxaborolane moiety ensures high reactivity and stability under coupling conditions, making it valuable in medicinal chemistry for building fluorinated aromatic scaffolds. It is also employed in the development of functional materials and ligands for catalysis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿3,190.00 |
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| 1.000 | 10-20 days | ฿7,980.00 |
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4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoic acid
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester precursor in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its trifluoromethyl and carboxylic acid functional groups enable selective transformations and facilitate the construction of biaryl structures with enhanced metabolic stability and lipophilicity. The presence of the dioxaborolane moiety ensures high reactivity and stability under coupling conditions, making it valuable in medicinal chemistry for building fluorinated aromatic scaffolds. It is also employed in the development of functional materials and ligands for catalysis.
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