tert-Butyl (4-bromo-2-(trifluoromethyl)benzyl)carbamate
98%
- Product Code: 129868
CAS:
1299483-40-1
| Molecular Weight: | 354.16 g./mol | Molecular Formula: | C₁₃H₁₅BrF₃NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32176810 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules that target central nervous system disorders. Its structure allows for selective modification in drug design, especially in creating analogs with enhanced metabolic stability. Commonly employed in medicinal chemistry for constructing complex benzylamine derivatives. The tert-butyl carbamate (Boc) group serves as a protecting group for amines during multi-step syntheses, enabling controlled deprotection under mild acidic conditions. Also utilized in the preparation of kinase inhibitors and receptor modulators due to the electron-withdrawing nature of the trifluoromethyl and bromo substituents, which influence binding affinity and pharmacokinetic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿15,540.00 |
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| 0.250 | 10-20 days | ฿5,280.00 |
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tert-Butyl (4-bromo-2-(trifluoromethyl)benzyl)carbamate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules that target central nervous system disorders. Its structure allows for selective modification in drug design, especially in creating analogs with enhanced metabolic stability. Commonly employed in medicinal chemistry for constructing complex benzylamine derivatives. The tert-butyl carbamate (Boc) group serves as a protecting group for amines during multi-step syntheses, enabling controlled deprotection under mild acidic conditions. Also utilized in the preparation of kinase inhibitors and receptor modulators due to the electron-withdrawing nature of the trifluoromethyl and bromo substituents, which influence binding affinity and pharmacokinetic properties.
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