5-(Bromomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
98%
- Product Code: 130189
CAS:
1312023-72-5
| Molecular Weight: | 351.15 g./mol | Molecular Formula: | C₁₄H₁₁BrN₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD34601661 | |
| Melting Point: | Boiling Point: | 583.1±50.0 °C(Predicted) | |
| Density: | 1.745±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its bromomethyl functional group allows for efficient conjugation to other molecules, enabling the development of PROTACs (proteolysis-targeting chimeras) that direct specific proteins for degradation. This compound is valuable in oncology and immunology drug discovery due to its role in enhancing selectivity and potency of therapeutic agents. It is also employed in the preparation of analogs for structure-activity relationship studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 0.100 | 10-20 days | £102.57 |
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| 1.000 | 10-20 days | £468.87 |
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| 0.250 | 10-20 days | £173.89 |
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5-(Bromomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its bromomethyl functional group allows for efficient conjugation to other molecules, enabling the development of PROTACs (proteolysis-targeting chimeras) that direct specific proteins for degradation. This compound is valuable in oncology and immunology drug discovery due to its role in enhancing selectivity and potency of therapeutic agents. It is also employed in the preparation of analogs for structure-activity relationship studies.
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