3-(7-Fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
97%
- Product Code: 130550
CAS:
2287267-33-6
| Molecular Weight: | 262.24 g./mol | Molecular Formula: | C₁₃H₁₁FN₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31746002 | |
| Melting Point: | Boiling Point: | 545.3±50.0 °C(Predicted) | |
| Density: | Storage Condition: | Room temperature, seal, inert gas |
Product Description:
Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of immunomodulatory drugs that promote the degradation of disease-causing proteins in conditions like multiple myeloma and other hematological cancers. Its structure enables selective binding to cereblon, enhancing the ubiquitination and subsequent degradation of specific cellular proteins involved in tumor growth and inflammation. Due to its potent biological activity, it is primarily used in preclinical studies and drug discovery programs focused on oncology and immune-mediated diseases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿14,690.00 |
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| 250mg | 10-20 days | ฿24,960.00 |
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3-(7-Fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of immunomodulatory drugs that promote the degradation of disease-causing proteins in conditions like multiple myeloma and other hematological cancers. Its structure enables selective binding to cereblon, enhancing the ubiquitination and subsequent degradation of specific cellular proteins involved in tumor growth and inflammation. Due to its potent biological activity, it is primarily used in preclinical studies and drug discovery programs focused on oncology and immune-mediated diseases.
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