2,6-Dichloro-3-(trimethylstannyl)pyridine

95%

  • Product Code: 131404
  CAS:    148493-35-0
Molecular Weight: 310.8 g./mol Molecular Formula: C₈H₁₁Cl₂NSn
EC Number: MDL Number: MFCD22056717
Melting Point: Boiling Point: 287.7±50.0 °C(Predicted)
Density: Storage Condition: 2-8°C, Sealed, Inert Gas
Product Description: Used primarily as an intermediate in the synthesis of pharmaceutical compounds, especially in the development of kinase inhibitors and other biologically active molecules. Its organotin functionality allows it to participate in palladium-catalyzed cross-coupling reactions, such as Stille coupling, enabling the formation of carbon-carbon bonds in complex heterocyclic systems. This makes it valuable in medicinal chemistry for constructing drug candidates targeting cancer, inflammation, and central nervous system disorders. Due to the toxicity associated with tin residues, it is generally not present in final drug products but serves a critical role in early synthetic steps where selective functionalization of the pyridine ring is required.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days ฿7,850.00
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-
0.250 10-20 days ฿18,030.00
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-
2,6-Dichloro-3-(trimethylstannyl)pyridine
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, especially in the development of kinase inhibitors and other biologically active molecules. Its organotin functionality allows it to participate in palladium-catalyzed cross-coupling reactions, such as Stille coupling, enabling the formation of carbon-carbon bonds in complex heterocyclic systems. This makes it valuable in medicinal chemistry for constructing drug candidates targeting cancer, inflammation, and central nervous system disorders. Due to the toxicity associated with tin residues, it is generally not present in final drug products but serves a critical role in early synthetic steps where selective functionalization of the pyridine ring is required.
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