3,3-Difluoropyrrolidine-1-sulfonyl chloride
95%
- Product Code: 131544
CAS:
1187160-31-1
| Molecular Weight: | 205.61 g./mol | Molecular Formula: | C₄H₆ClF₂NO₂S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD27918725 | |
| Melting Point: | Boiling Point: | 260.7±40.0 °C(Predicted) | |
| Density: | 1.63±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its structure enables the introduction of a difluorinated pyrrolidine moiety, which can enhance metabolic stability, membrane permeability, and binding affinity in drug molecules. Commonly employed in the development of protease inhibitors and kinase inhibitors due to its ability to mimic peptide bonds and influence conformational rigidity. Also utilized in the preparation of sulfonamide derivatives through reactions with amines, enabling the expansion of chemical diversity in medicinal chemistry research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿15,450.00 |
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| 250mg | 10-20 days | ฿26,250.00 |
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3,3-Difluoropyrrolidine-1-sulfonyl chloride
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its structure enables the introduction of a difluorinated pyrrolidine moiety, which can enhance metabolic stability, membrane permeability, and binding affinity in drug molecules. Commonly employed in the development of protease inhibitors and kinase inhibitors due to its ability to mimic peptide bonds and influence conformational rigidity. Also utilized in the preparation of sulfonamide derivatives through reactions with amines, enabling the expansion of chemical diversity in medicinal chemistry research.
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