(4-((tert-Butyldimethylsilyl)oxy)-2,6-difluorophenyl)boronic acid
98%
- Product Code: 131606
CAS:
2096341-77-2
| Molecular Weight: | 288.17 g./mol | Molecular Formula: | C₁₂H₁₉BF₂O₃Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD19237185 | |
| Melting Point: | Boiling Point: | 317.7±52.0 °C(Predicted) | |
| Density: | 1.12±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. The silyl-protected phenol group provides a handle for further functionalization or deprotection under mild conditions, making it valuable in multi-step organic syntheses. Commonly employed in medicinal chemistry for constructing fluorinated aromatic systems with improved metabolic stability and binding affinity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿2,310.00 |
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| 250mg | 10-20 days | ฿3,850.00 |
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| 1g | 10-20 days | ฿10,680.00 |
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(4-((tert-Butyldimethylsilyl)oxy)-2,6-difluorophenyl)boronic acid
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. The silyl-protected phenol group provides a handle for further functionalization or deprotection under mild conditions, making it valuable in multi-step organic syntheses. Commonly employed in medicinal chemistry for constructing fluorinated aromatic systems with improved metabolic stability and binding affinity.
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