Methyl 4-(3-chloro-4-(3-cyclopropylureido)phenoxy) -7-methoxyquinoline-6-carboxylate
95%
- Product Code: 131755
CAS:
417717-20-5
| Molecular Weight: | 441.86 g./mol | Molecular Formula: | C₂₂H₂₀ClN₃O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32644301 | |
| Melting Point: | Boiling Point: | 592.0±50.0 °C(Predicted) | |
| Density: | 1.42±0.1 g/cm3(Predicted) | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways involved in tumor growth and angiogenesis. Commonly applied in research and development of pharmaceuticals for non-small cell lung cancer and other solid tumors. Its structure enables selective inhibition of epidermal growth factor receptor (EGFR) mutants, including T790M and L858R, making it valuable in overcoming drug resistance in certain cancers. Also utilized in preclinical studies to evaluate antitumor efficacy and pharmacokinetic properties of novel oncology drug candidates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿10,380.00 |
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| 0.250 | 10-20 days | ฿17,640.00 |
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| 1.000 | 10-20 days | ฿47,620.00 |
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Methyl 4-(3-chloro-4-(3-cyclopropylureido)phenoxy) -7-methoxyquinoline-6-carboxylate
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways involved in tumor growth and angiogenesis. Commonly applied in research and development of pharmaceuticals for non-small cell lung cancer and other solid tumors. Its structure enables selective inhibition of epidermal growth factor receptor (EGFR) mutants, including T790M and L858R, making it valuable in overcoming drug resistance in certain cancers. Also utilized in preclinical studies to evaluate antitumor efficacy and pharmacokinetic properties of novel oncology drug candidates.
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