Spiramide8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone
98%
- Product Code: 133758
CAS:
510-74-7
| Molecular Weight: | 383.46 g./mol | Molecular Formula: | C₂₂H₂₆FN₃O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | 176 - 179 °C | Boiling Point: | |
| Density: | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used primarily in pharmaceutical research as a potent sigma receptor ligand, particularly showing high affinity for the sigma-1 receptor subtype. This activity makes it valuable in studying neurological disorders such as neuropathic pain, depression, and neurodegenerative diseases like Alzheimer's. Its spirocyclic structure and fluorinated aromatic group enhance blood-brain barrier penetration, making it suitable for central nervous system-targeted drug development. It is also employed as a reference compound in receptor binding assays and for validating imaging agents in positron emission tomography (PET) studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | Ft64,520.78 |
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| 0.010 | 10-20 days | Ft104,031.88 |
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Spiramide8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone
Used primarily in pharmaceutical research as a potent sigma receptor ligand, particularly showing high affinity for the sigma-1 receptor subtype. This activity makes it valuable in studying neurological disorders such as neuropathic pain, depression, and neurodegenerative diseases like Alzheimer's. Its spirocyclic structure and fluorinated aromatic group enhance blood-brain barrier penetration, making it suitable for central nervous system-targeted drug development. It is also employed as a reference compound in receptor binding assays and for validating imaging agents in positron emission tomography (PET) studies.
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