AZD-9291 mesylate
10mM in DMSO
- Product Code: 134256
CAS:
1421373-66-1
| Molecular Weight: | 595.71 g./mol | Molecular Formula: | C₂₉H₃₇N₇O₅S |
|---|---|---|---|
| EC Number: | 200-064-1 | MDL Number: | MFCD28137994 |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used in targeted cancer therapy, particularly for non-small cell lung cancer (NSCLC) with EGFR mutations. It acts as a third-generation EGFR tyrosine kinase inhibitor, selectively targeting both T790M resistance mutations and activating EGFR mutations while sparing wild-type EGFR. This selectivity reduces side effects and improves efficacy in patients who have developed resistance to earlier EGFR inhibitors. The mesylate salt form enhances solubility and bioavailability, supporting oral dosing in clinical settings.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿1,860.00 |
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AZD-9291 mesylate
Used in targeted cancer therapy, particularly for non-small cell lung cancer (NSCLC) with EGFR mutations. It acts as a third-generation EGFR tyrosine kinase inhibitor, selectively targeting both T790M resistance mutations and activating EGFR mutations while sparing wild-type EGFR. This selectivity reduces side effects and improves efficacy in patients who have developed resistance to earlier EGFR inhibitors. The mesylate salt form enhances solubility and bioavailability, supporting oral dosing in clinical settings.
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