Apatinib Mesylate
10mM in DMSO
- Product Code: 134319
CAS:
1218779-75-9
| Molecular Weight: | 493.58 g./mol | Molecular Formula: | C₂₅H₂₇N₅O₄S |
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| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used primarily in the treatment of advanced gastric or gastroesophageal junction adenocarcinoma, especially in patients who have failed at least two prior chemotherapy regimens. It functions as a selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2), blocking angiogenesis and thereby suppressing tumor growth and metastasis. Investigated in other solid tumors including hepatocellular carcinoma, non-small cell lung cancer, and breast cancer, often in combination with chemotherapy or immunotherapy. Its oral bioavailability allows for convenient outpatient treatment, and it has shown efficacy in extending progression-free and overall survival in clinical studies. Due to its mechanism, it may cause hypertension, proteinuria, and hand-foot syndrome as common side effects.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿28,360.00 |
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Apatinib Mesylate
Used primarily in the treatment of advanced gastric or gastroesophageal junction adenocarcinoma, especially in patients who have failed at least two prior chemotherapy regimens. It functions as a selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2), blocking angiogenesis and thereby suppressing tumor growth and metastasis. Investigated in other solid tumors including hepatocellular carcinoma, non-small cell lung cancer, and breast cancer, often in combination with chemotherapy or immunotherapy. Its oral bioavailability allows for convenient outpatient treatment, and it has shown efficacy in extending progression-free and overall survival in clinical studies. Due to its mechanism, it may cause hypertension, proteinuria, and hand-foot syndrome as common side effects.
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