AMN-107 HCl
10mM in DMSO
- Product Code: 134338
CAS:
923288-95-3
| Molecular Weight: | 565.98 g./mol | Molecular Formula: | C₂₈H₂₂F₃N₇O·HCl |
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| Density: | Storage Condition: | -20°C |
Product Description:
Used in the treatment of chronic myeloid leukemia (CML), particularly in patients who are resistant or intolerant to prior therapy including imatinib. It functions as a selective Bcr-Abl tyrosine kinase inhibitor, effectively targeting the abnormal protein responsible for the uncontrolled growth of leukemic cells. Its ability to maintain potency against several imatinib-resistant mutations makes it valuable in second-line therapy. It is taken orally and designed to achieve sustained inhibition of Bcr-Abl signaling, helping to induce and maintain hematologic and cytogenetic responses in affected patients.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿5,580.00 |
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AMN-107 HCl
Used in the treatment of chronic myeloid leukemia (CML), particularly in patients who are resistant or intolerant to prior therapy including imatinib. It functions as a selective Bcr-Abl tyrosine kinase inhibitor, effectively targeting the abnormal protein responsible for the uncontrolled growth of leukemic cells. Its ability to maintain potency against several imatinib-resistant mutations makes it valuable in second-line therapy. It is taken orally and designed to achieve sustained inhibition of Bcr-Abl signaling, helping to induce and maintain hematologic and cytogenetic responses in affected patients.
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