AT-13148
10mM in DMSO
- Product Code: 134400
CAS:
1056901-62-2
| Molecular Weight: | 313.78 g./mol | Molecular Formula: | C₁₇H₁₆ClN₃O |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
AT-13148 is a potent inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK), making it a valuable tool in research related to cellular motility, cytoskeletal organization, and signal transduction. It has been investigated for its potential in oncology due to its ability to suppress tumor cell invasion and metastasis by interfering with ROCK-mediated pathways. The compound shows activity against several cancer cell lines in preclinical models, particularly in reducing cell migration and inducing apoptosis. Its application extends to studying cardiovascular diseases, where ROCK inhibition can influence vascular tone and remodeling. Due to its kinase inhibitory profile, AT-13148 is primarily used in experimental settings to dissect pathways involved in cancer progression and cellular contraction, rather than as a therapeutic agent in clinical use.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,480.00 |
+
-
|
AT-13148
AT-13148 is a potent inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK), making it a valuable tool in research related to cellular motility, cytoskeletal organization, and signal transduction. It has been investigated for its potential in oncology due to its ability to suppress tumor cell invasion and metastasis by interfering with ROCK-mediated pathways. The compound shows activity against several cancer cell lines in preclinical models, particularly in reducing cell migration and inducing apoptosis. Its application extends to studying cardiovascular diseases, where ROCK inhibition can influence vascular tone and remodeling. Due to its kinase inhibitory profile, AT-13148 is primarily used in experimental settings to dissect pathways involved in cancer progression and cellular contraction, rather than as a therapeutic agent in clinical use.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :