A-438079 HCl
10mM in DMSO
- Product Code: 134416
CAS:
899431-18-6
| Molecular Weight: | 342.61 g./mol | Molecular Formula: | C₁₃H₁₀Cl₃N₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09971142 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
A-438079 HCl is a selective antagonist of the P2X7 receptor, a subtype of ATP-gated ion channels involved in inflammatory responses. It is primarily used in research settings to study the role of P2X7 receptors in neuroinflammation, pain signaling, and immune cell activation. Due to its ability to inhibit NLRP3 inflammasome activation, it has been investigated in models of chronic pain, neurodegenerative diseases such as Alzheimer's, and autoimmune conditions. Its selectivity makes it a valuable tool for probing P2X7-mediated pathways without significant off-target effects on other purinergic receptors. A-438079 HCl is commonly applied in in vitro and in vivo studies to assess the therapeutic potential of blocking P2X7 signaling in inflammation and tissue damage.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,840.00 |
+
-
|
A-438079 HCl
A-438079 HCl is a selective antagonist of the P2X7 receptor, a subtype of ATP-gated ion channels involved in inflammatory responses. It is primarily used in research settings to study the role of P2X7 receptors in neuroinflammation, pain signaling, and immune cell activation. Due to its ability to inhibit NLRP3 inflammasome activation, it has been investigated in models of chronic pain, neurodegenerative diseases such as Alzheimer's, and autoimmune conditions. Its selectivity makes it a valuable tool for probing P2X7-mediated pathways without significant off-target effects on other purinergic receptors. A-438079 HCl is commonly applied in in vitro and in vivo studies to assess the therapeutic potential of blocking P2X7 signaling in inflammation and tissue damage.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :