Alloc-Val-Ala-PAB-OH
≥97%(LC&N)
- Product Code: 137288
CAS:
1343407-91-9
Molecular Weight: | 377.44 g./mol | Molecular Formula: | C₁₉H₂₇N₃O₅ |
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EC Number: | MDL Number: | ||
Melting Point: | 227 °C | Boiling Point: | |
Density: | Storage Condition: | Room temperature |
Product Description:
Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. The Alloc group acts as a protecting group that can be selectively removed under mild conditions, allowing precise control during synthesis. The PAB (para-aminobenzyloxycarbonyl) spacer enables efficient release of the drug payload inside the cell through enzymatic cleavage, enhancing therapeutic efficacy while minimizing off-target effects. Commonly employed in the development of novel anticancer agents where controlled drug activation is critical.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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50mg | 10-20 days | ฿4,850.00 |
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Alloc-Val-Ala-PAB-OH
Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. The Alloc group acts as a protecting group that can be selectively removed under mild conditions, allowing precise control during synthesis. The PAB (para-aminobenzyloxycarbonyl) spacer enables efficient release of the drug payload inside the cell through enzymatic cleavage, enhancing therapeutic efficacy while minimizing off-target effects. Commonly employed in the development of novel anticancer agents where controlled drug activation is critical.
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