Alloc-Val-Ala-PAB-OH

≥97%(LC&N)

  • Product Code: 137288
  CAS:    1343407-91-9
Molecular Weight: 377.44 g./mol Molecular Formula: C₁₉H₂₇N₃O₅
EC Number: MDL Number:
Melting Point: 227 °C Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. The Alloc group acts as a protecting group that can be selectively removed under mild conditions, allowing precise control during synthesis. The PAB (para-aminobenzyloxycarbonyl) spacer enables efficient release of the drug payload inside the cell through enzymatic cleavage, enhancing therapeutic efficacy while minimizing off-target effects. Commonly employed in the development of novel anticancer agents where controlled drug activation is critical.
Sizes / Availability / Pricing:
Size Availability Price Quantity
50mg 10-20 days ฿4,850.00
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Alloc-Val-Ala-PAB-OH
Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. The Alloc group acts as a protecting group that can be selectively removed under mild conditions, allowing precise control during synthesis. The PAB (para-aminobenzyloxycarbonyl) spacer enables efficient release of the drug payload inside the cell through enzymatic cleavage, enhancing therapeutic efficacy while minimizing off-target effects. Commonly employed in the development of novel anticancer agents where controlled drug activation is critical.
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