Acetylthio-PEG4-Alkyne

>98%(GC)

  • Product Code: 137297
  CAS:    1422540-88-2
Molecular Weight: 290.37 g./mol Molecular Formula: C₁₃H₂₂O₅S
EC Number: MDL Number:
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Density: Storage Condition: Room temperature
Product Description: Used in bioconjugation reactions, particularly in click chemistry applications. Its alkyne group reacts efficiently with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling site-specific labeling of biomolecules such as peptides, proteins, and antibodies. The PEG4 spacer enhances solubility in aqueous systems and reduces non-specific binding, improving the bioavailability and stability of conjugated products. The acetylthio group allows for reversible attachment to thiol-reactive sites, making it useful in the development of cleavable linkers for drug delivery systems and targeted therapeutics. Commonly employed in the synthesis of antibody-drug conjugates (ADCs) and diagnostic probes.
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Size Availability Price Quantity
0.050 10-20 days ฿15,190.00
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Acetylthio-PEG4-Alkyne
Used in bioconjugation reactions, particularly in click chemistry applications. Its alkyne group reacts efficiently with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling site-specific labeling of biomolecules such as peptides, proteins, and antibodies. The PEG4 spacer enhances solubility in aqueous systems and reduces non-specific binding, improving the bioavailability and stability of conjugated products. The acetylthio group allows for reversible attachment to thiol-reactive sites, making it useful in the development of cleavable linkers for drug delivery systems and targeted therapeutics. Commonly employed in the synthesis of antibody-drug conjugates (ADCs) and diagnostic probes.
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