Anti-CLDN18.2 Reference Antibody (zolbetuximab)
- Product Code: 139932
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| Density: | Storage Condition: | -20℃ |
Product Description:
Used in targeted cancer therapy, particularly for gastric and gastroesophageal junction cancers that overexpress the CLDN18.2 protein. It binds specifically to CLDN18.2 on tumor cells, triggering immune-mediated cell destruction through mechanisms like antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Currently evaluated in clinical trials to assess its efficacy in combination with chemotherapy, showing promise in improving progression-free and overall survival in patients with CLDN18.2-positive tumors. Its high specificity allows for targeted treatment with potentially fewer off-target effects compared to conventional chemotherapy.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50μg | 10-20 days | ฿4,980.00 |
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Anti-CLDN18.2 Reference Antibody (zolbetuximab)
Used in targeted cancer therapy, particularly for gastric and gastroesophageal junction cancers that overexpress the CLDN18.2 protein. It binds specifically to CLDN18.2 on tumor cells, triggering immune-mediated cell destruction through mechanisms like antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Currently evaluated in clinical trials to assess its efficacy in combination with chemotherapy, showing promise in improving progression-free and overall survival in patients with CLDN18.2-positive tumors. Its high specificity allows for targeted treatment with potentially fewer off-target effects compared to conventional chemotherapy.
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