Anti-TNFSF5 / CD40L / CD154 Reference Antibody (ruplizumab)
- Product Code: 140610
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Product Description:
Used in research and development for immunological disorders, this antibody targets CD40 ligand (CD40L), a protein involved in immune cell signaling. By blocking CD40L, it modulates T-cell and B-cell interactions, which helps in studying autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis. It has been investigated for its potential to reduce inflammation and prevent immune-mediated tissue damage. Additionally, it serves as a reference in assays evaluating anti-CD40L therapeutics and in flow cytometry or ELISA to detect CD40L expression. Its use remains primarily non-clinical, supporting drug development and mechanistic studies in immunology.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50μg | 10-20 days | $197.89 |
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Anti-TNFSF5 / CD40L / CD154 Reference Antibody (ruplizumab)
Used in research and development for immunological disorders, this antibody targets CD40 ligand (CD40L), a protein involved in immune cell signaling. By blocking CD40L, it modulates T-cell and B-cell interactions, which helps in studying autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis. It has been investigated for its potential to reduce inflammation and prevent immune-mediated tissue damage. Additionally, it serves as a reference in assays evaluating anti-CD40L therapeutics and in flow cytometry or ELISA to detect CD40L expression. Its use remains primarily non-clinical, supporting drug development and mechanistic studies in immunology.
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