tert-Butyl 7-bromo-5-(trifluoromethoxy)-1H-indole-1-carboxylate
95%
- Product Code: 141418
CAS:
2940951-92-6
| Molecular Weight: | 380.16 g./mol | Molecular Formula: | C₁₄H₁₃BrF₃NO₃ |
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| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of indole-based drugs targeting neurological and psychiatric disorders. Its protected indole structure allows selective functionalization at specific positions, making it valuable in medicinal chemistry for building complex molecules. Commonly employed in cross-coupling reactions due to the bromo substituent, enabling the formation of carbon-carbon bonds for drug scaffold diversification. The trifluoromethoxy group enhances metabolic stability and lipophilicity, beneficial for improving drug bioavailability. Widely applied in research settings for generating analogs in structure-activity relationship (SAR) studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿15,830.00 |
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| 250mg | 10-20 days | ฿26,900.00 |
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| 1g | 10-20 days | ฿72,600.00 |
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tert-Butyl 7-bromo-5-(trifluoromethoxy)-1H-indole-1-carboxylate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of indole-based drugs targeting neurological and psychiatric disorders. Its protected indole structure allows selective functionalization at specific positions, making it valuable in medicinal chemistry for building complex molecules. Commonly employed in cross-coupling reactions due to the bromo substituent, enabling the formation of carbon-carbon bonds for drug scaffold diversification. The trifluoromethoxy group enhances metabolic stability and lipophilicity, beneficial for improving drug bioavailability. Widely applied in research settings for generating analogs in structure-activity relationship (SAR) studies.
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