tert-Butyl (3-cyano-7-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophen-2-yl)carbamate
≥95%
- Product Code: 141676
CAS:
2761968-90-3
| Molecular Weight: | 418.29 g./mol | Molecular Formula: | C₂₀H₂₄BFN₂O₄S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 514.4±50.0 °C(Predicted) | |
| Density: | 1.25±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C |
Product Description:
Used as an intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical development. The presence of the cyano and fluoro groups enhances reactivity and selectivity in coupling processes. The boronate ester allows for efficient carbon-carbon bond formation, making it valuable in constructing complex aromatic systems found in drug candidates. Commonly applied in the preparation of kinase inhibitors and other therapeutic agents requiring substituted benzo[b]thiophene scaffolds. Its tert-butyl carbamate (Boc) protecting group ensures amine functionality remains intact during reactions, enabling sequential synthetic strategies in medicinal chemistry.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | €113.65 |
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| 0.250 | 10-20 days | €193.31 |
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| 1.000 | 10-20 days | €499.73 |
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tert-Butyl (3-cyano-7-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophen-2-yl)carbamate
Used as an intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical development. The presence of the cyano and fluoro groups enhances reactivity and selectivity in coupling processes. The boronate ester allows for efficient carbon-carbon bond formation, making it valuable in constructing complex aromatic systems found in drug candidates. Commonly applied in the preparation of kinase inhibitors and other therapeutic agents requiring substituted benzo[b]thiophene scaffolds. Its tert-butyl carbamate (Boc) protecting group ensures amine functionality remains intact during reactions, enabling sequential synthetic strategies in medicinal chemistry.
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