5-Bromo-2'-deoxy-5'-DMT-D-uridine 3'-CE phosphoramidite
≥95%
- Product Code: 142871
CAS:
63660-21-9
| Molecular Weight: | 809.7 g./mol | Molecular Formula: | C₃₉H₄₆BrN₄O₈P |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00036355 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in solid-phase oligonucleotide synthesis, this compound enables the site-specific incorporation of brominated deoxyuridine into DNA strands. The bromine moiety acts as a handle for downstream conjugation or as a radiolabel precursor in molecular imaging. It is particularly valuable in probe development for fluorescence in situ hybridization (FISH) and in creating photo-crosslinkable DNA for studying nucleic acid-protein interactions. The DMT group ensures controlled coupling efficiency, while the phosphoramidite functionality allows automated synthesis with high yield and purity. Commonly applied in antisense oligonucleotide research and nucleic acid diagnostics where modified bases enhance stability or enable functional tagging.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | $428.12 |
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5-Bromo-2'-deoxy-5'-DMT-D-uridine 3'-CE phosphoramidite
Used in solid-phase oligonucleotide synthesis, this compound enables the site-specific incorporation of brominated deoxyuridine into DNA strands. The bromine moiety acts as a handle for downstream conjugation or as a radiolabel precursor in molecular imaging. It is particularly valuable in probe development for fluorescence in situ hybridization (FISH) and in creating photo-crosslinkable DNA for studying nucleic acid-protein interactions. The DMT group ensures controlled coupling efficiency, while the phosphoramidite functionality allows automated synthesis with high yield and purity. Commonly applied in antisense oligonucleotide research and nucleic acid diagnostics where modified bases enhance stability or enable functional tagging.
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