2,8-Bis(trifluoromethyl)-4-hydroxyquinoline
98%
- Product Code: 143129
Alias:
2,8-bis(trifluoromethyl)-4-hydroxyquinoline
CAS:
35853-41-9
| Molecular Weight: | 281.15 g./mol | Molecular Formula: | C₁₁H₅F₆NO |
|---|---|---|---|
| EC Number: | 252-762-0 | MDL Number: | MFCD00075091 |
| Melting Point: | 130-134 °C(lit.) | Boiling Point: | |
| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium. Its trifluoromethyl groups enhance metabolic stability and membrane permeability, improving the pharmacokinetic profile of the final drug compound. Also employed in research for antimicrobial and anticancer agents due to its ability to intercalate DNA and inhibit topoisomerase enzymes. Shows promise in agrochemical applications as a fungicidal agent in crop protection.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿154.00 |
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| 5g | 10-20 days | ฿418.00 |
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| 25g | 10-20 days | ฿3,230.00 |
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| 100g | 10-20 days | ฿12,020.00 |
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| 500g | 10-20 days | ฿46,790.00 |
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2,8-Bis(trifluoromethyl)-4-hydroxyquinoline
Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium. Its trifluoromethyl groups enhance metabolic stability and membrane permeability, improving the pharmacokinetic profile of the final drug compound. Also employed in research for antimicrobial and anticancer agents due to its ability to intercalate DNA and inhibit topoisomerase enzymes. Shows promise in agrochemical applications as a fungicidal agent in crop protection.
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