1-Boc-4-bromomethylpiperidine
98%
- Product Code: 143464
Alias:
1-Boc-4-Bromomethylpiperidine
CAS:
158407-04-6
| Molecular Weight: | 278.19 g./mol | Molecular Formula: | C₁₁H₂₀BrNO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD04115538 | |
| Melting Point: | Boiling Point: | 318.3±15.0 °C | |
| Density: | 1.270±0.06 g/cm3 | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) containing piperidine moieties. The Boc-protected amine and bromomethyl functional group allow for selective reactions—Boc group provides stability during synthesis and can be easily removed under acidic conditions, while the bromomethyl group serves as a reactive site for nucleophilic substitution, enabling coupling with other molecules such as amines or heterocycles. Commonly employed in the preparation of drug candidates targeting central nervous system disorders, including analgesics, antidepressants, and antipsychotics. Its structure facilitates modular synthesis in medicinal chemistry, making it valuable in combinatorial and parallel synthesis for lead optimization.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿168.00 |
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| 1.000 G | 10-20 days | ฿310.00 |
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| 5.000 G | 10-20 days | ฿1,000.00 |
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| 25.000 G | 10-20 days | ฿4,680.00 |
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| 100.000 G | 10-20 days | ฿18,610.00 |
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| 500.000 G | 10-20 days | ฿82,480.00 |
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1-Boc-4-bromomethylpiperidine
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) containing piperidine moieties. The Boc-protected amine and bromomethyl functional group allow for selective reactions—Boc group provides stability during synthesis and can be easily removed under acidic conditions, while the bromomethyl group serves as a reactive site for nucleophilic substitution, enabling coupling with other molecules such as amines or heterocycles. Commonly employed in the preparation of drug candidates targeting central nervous system disorders, including analgesics, antidepressants, and antipsychotics. Its structure facilitates modular synthesis in medicinal chemistry, making it valuable in combinatorial and parallel synthesis for lead optimization.
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