1-(Boc-amino)cyclopropanecarboxylic acid
98%
- Product Code: 144375
CAS:
88950-64-5
| Molecular Weight: | 201.22 g./mol | Molecular Formula: | C₉H₁₅NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00083257 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Widely used in organic synthesis, particularly in the preparation of cyclopropane-containing peptides and peptidomimetics. Its structure features both a protected amine (Boc group) and a carboxylic acid, making it ideal for peptide coupling reactions where controlled stepwise assembly is required. The cyclopropane ring introduces conformational rigidity, which is valuable in medicinal chemistry for enhancing metabolic stability, improving target selectivity, and modulating the pharmacokinetic properties of drug candidates. Commonly employed in the development of bioactive molecules, including protease inhibitors and receptor agonists/antagonists. Also serves as a building block in solid-phase peptide synthesis and combinatorial chemistry due to its stability and compatibility with standard coupling reagents.
Product Specification:
| Test | Specification |
|---|---|
| Purity | 98-100 |
| Melting Point Degree Celsius | 173-181 |
| Appearance | White to Off-white Powder crystals |
| HNMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 G | 10-20 days | ฿168.00 |
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| 5.000 G | 10-20 days | ฿590.00 |
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| 100.000 G | 10-20 days | ฿9,990.00 |
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| 500.000 G | 10-20 days | ฿41,000.00 |
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| 25.000 G | 10-20 days | ฿2,810.00 |
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1-(Boc-amino)cyclopropanecarboxylic acid
Widely used in organic synthesis, particularly in the preparation of cyclopropane-containing peptides and peptidomimetics. Its structure features both a protected amine (Boc group) and a carboxylic acid, making it ideal for peptide coupling reactions where controlled stepwise assembly is required. The cyclopropane ring introduces conformational rigidity, which is valuable in medicinal chemistry for enhancing metabolic stability, improving target selectivity, and modulating the pharmacokinetic properties of drug candidates. Commonly employed in the development of bioactive molecules, including protease inhibitors and receptor agonists/antagonists. Also serves as a building block in solid-phase peptide synthesis and combinatorial chemistry due to its stability and compatibility with standard coupling reagents.
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| Stable in pH range | - |
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