5-[4’-Bromomethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole
96%
- Product Code: 144426
CAS:
124750-51-2
| Molecular Weight: | 557.48 g./mol | Molecular Formula: | C₃₃H₂₅BrN₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00665221 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8℃, dry |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of sartan-class antihypertensive drugs. Its structure allows for the introduction of biphenyl and tetrazole moieties, which are critical for biological activity in blocking the angiotensin II receptor. The bromomethyl group enables alkylation reactions to form carbon-nitrogen or carbon-oxygen bonds, facilitating the assembly of complex drug molecules. Commonly employed in pharmaceutical research and development for optimizing potency and pharmacokinetic properties of cardiovascular medications.
Product Specification:
| Test | Specification |
|---|---|
| PUITY | 95.5-100 |
| APPEARANCE | WHITE TO OFF-WHITE POWDER OR CRYSTALS |
| INFRARED SPECTRUM | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 G | 10-20 days | ฿143.00 |
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| 5.000 G | 10-20 days | ฿300.00 |
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| 25.000 G | 10-20 days | ฿600.00 |
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| 100.000 G | 10-20 days | ฿2,010.00 |
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| 500.000 G | 10-20 days | ฿10,000.00 |
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5-[4’-Bromomethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of sartan-class antihypertensive drugs. Its structure allows for the introduction of biphenyl and tetrazole moieties, which are critical for biological activity in blocking the angiotensin II receptor. The bromomethyl group enables alkylation reactions to form carbon-nitrogen or carbon-oxygen bonds, facilitating the assembly of complex drug molecules. Commonly employed in pharmaceutical research and development for optimizing potency and pharmacokinetic properties of cardiovascular medications.
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| Stable in pH range | - |
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