tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate
97%
- Product Code: 145293
CAS:
373604-28-5
| Molecular Weight: | 219.25 g./mol | Molecular Formula: | C₁₀H₁₈FNO₃ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 300.8°C | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. Its structure supports the creation of bioactive molecules due to the presence of a fluorinated piperidine core, which enhances metabolic stability and membrane permeability. Commonly employed in the preparation of selective receptor modulators, including those targeting serotonin and dopamine receptors. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the hydroxy and fluoro groups allow for further functionalization. Its protected carboxylate (Boc) group enables controlled deprotection and coupling in multi-step synthetic routes.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | $107.91 |
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| 5g | 10-20 days | $319.11 |
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tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. Its structure supports the creation of bioactive molecules due to the presence of a fluorinated piperidine core, which enhances metabolic stability and membrane permeability. Commonly employed in the preparation of selective receptor modulators, including those targeting serotonin and dopamine receptors. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the hydroxy and fluoro groups allow for further functionalization. Its protected carboxylate (Boc) group enables controlled deprotection and coupling in multi-step synthetic routes.
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