tert-Butyl (cis-3-hydroxycyclobutyl)carbamate

97%

  • Product Code: 146163
  CAS:    389890-43-1
Molecular Weight: 187.24 g./mol Molecular Formula: C₉H₁₇NO₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules where a protected cyclobutylamine scaffold is required. The tert-butyl carbamate (Boc) group provides stability during multi-step reactions and can be easily removed under mild acidic conditions, allowing for further functionalization. The cis-hydroxy substituent on the cyclobutane ring offers a handle for additional derivatization, making this compound valuable in medicinal chemistry for constructing constrained ring systems that can enhance potency, selectivity, or metabolic stability in drug candidates. Commonly employed in the preparation of kinase inhibitors, CNS-active agents, and other small-molecule therapeutics.
Sizes / Availability / Pricing:
Size Availability Price Quantity
5.000 10-20 days $112.27
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10.000 10-20 days $192.23
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25.000 10-20 days $398.06
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50.000 10-20 days $793.57
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100.000 10-20 days $1,568.01
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tert-Butyl (cis-3-hydroxycyclobutyl)carbamate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules where a protected cyclobutylamine scaffold is required. The tert-butyl carbamate (Boc) group provides stability during multi-step reactions and can be easily removed under mild acidic conditions, allowing for further functionalization. The cis-hydroxy substituent on the cyclobutane ring offers a handle for additional derivatization, making this compound valuable in medicinal chemistry for constructing constrained ring systems that can enhance potency, selectivity, or metabolic stability in drug candidates. Commonly employed in the preparation of kinase inhibitors, CNS-active agents, and other small-molecule therapeutics.
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