1-Boc-5,6-Dichloro-1H-indole
95%
- Product Code: 146186
CAS:
1209183-93-6
| Molecular Weight: | 286.15 g./mol | Molecular Formula: | C₁₃H₁₃Cl₂NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09909712 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical synthesis as a protected indole intermediate, particularly in the development of kinase inhibitors and other bioactive molecules. The Boc group provides nitrogen protection during coupling reactions, while the dichloro substitution allows for selective cross-coupling, such as Suzuki or Buchwald-Hartwig reactions, to build complex heterocyclic systems. Commonly employed in medicinal chemistry for optimizing lead compounds in drug discovery programs targeting cancer and inflammatory diseases. Its stability and reactivity profile make it suitable for multi-step syntheses requiring selective functionalization.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿1,300.00 |
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| 250mg | 10-20 days | ฿3,910.00 |
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1-Boc-5,6-Dichloro-1H-indole
Used in pharmaceutical synthesis as a protected indole intermediate, particularly in the development of kinase inhibitors and other bioactive molecules. The Boc group provides nitrogen protection during coupling reactions, while the dichloro substitution allows for selective cross-coupling, such as Suzuki or Buchwald-Hartwig reactions, to build complex heterocyclic systems. Commonly employed in medicinal chemistry for optimizing lead compounds in drug discovery programs targeting cancer and inflammatory diseases. Its stability and reactivity profile make it suitable for multi-step syntheses requiring selective functionalization.
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