tert-Butyl 2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate
97%
- Product Code: 146273
CAS:
114676-79-8
| Molecular Weight: | 199.25 g./mol | Molecular Formula: | C₁₀H₁₇NO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08693704 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as a protected chiral building block in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the bicyclic structure serves as a constrained amino alcohol or amine derivative. Its rigid framework helps control stereochemistry in drug molecules, improving selectivity and metabolic stability. Commonly employed in medicinal chemistry for constructing protease inhibitors, kinase inhibitors, and central nervous system agents. The tert-butyl carbamate (Boc) group allows for easy deprotection under mild acidic conditions, enabling sequential coupling reactions in multi-step syntheses. Also utilized in the preparation of peptidomimetics and other bioactive compounds requiring defined three-dimensional architecture.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿2,160.00 |
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| 250mg | 10-20 days | ฿6,520.00 |
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tert-Butyl 2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate
Used as a protected chiral building block in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the bicyclic structure serves as a constrained amino alcohol or amine derivative. Its rigid framework helps control stereochemistry in drug molecules, improving selectivity and metabolic stability. Commonly employed in medicinal chemistry for constructing protease inhibitors, kinase inhibitors, and central nervous system agents. The tert-butyl carbamate (Boc) group allows for easy deprotection under mild acidic conditions, enabling sequential coupling reactions in multi-step syntheses. Also utilized in the preparation of peptidomimetics and other bioactive compounds requiring defined three-dimensional architecture.
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