tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate
97%
- Product Code: 146326
CAS:
212127-83-8
| Molecular Weight: | 295.19 g./mol | Molecular Formula: | C₁₅H₂₆BNO₄ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group readily participates in palladium-catalyzed couplings with aryl or vinyl halides, making it valuable for constructing complex organic molecules, especially in drug discovery and development. The tert-butyl carbamate (Boc) protecting group stabilizes the pyrroline nitrogen during reactions and can be easily removed under mild acidic conditions when needed. This compound is particularly useful in the synthesis of nitrogen-containing heterocycles and functionalized pyrrolidines, which are common structural motifs in bioactive compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿880.00 |
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| 1g | 10-20 days | ฿2,050.00 |
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| 50g | 10-20 days | ฿0.00 |
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| 5g | 10-20 days | ฿7,330.00 |
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tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group readily participates in palladium-catalyzed couplings with aryl or vinyl halides, making it valuable for constructing complex organic molecules, especially in drug discovery and development. The tert-butyl carbamate (Boc) protecting group stabilizes the pyrroline nitrogen during reactions and can be easily removed under mild acidic conditions when needed. This compound is particularly useful in the synthesis of nitrogen-containing heterocycles and functionalized pyrrolidines, which are common structural motifs in bioactive compounds.
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