tert-Butyldiphenylsilane

98%

  • Product Code: 147637
  CAS:    33729-92-9
Molecular Weight: 240.42 g./mol Molecular Formula: C₁₆H₂₀Si
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, stored in inert gas
Product Description: Used as a silyl protecting group reagent in organic synthesis, particularly for alcohols and phenols. Its bulky structure provides high selectivity and stability under various reaction conditions, making it valuable in multi-step synthesis of complex molecules like pharmaceuticals and natural products. The tert-butyldiphenylsilyl (TBDPS) group offers strong resistance to hydrolysis and basic conditions, allowing selective deprotection in the presence of other silyl groups. Commonly employed in carbohydrate chemistry, nucleoside synthesis, and peptide modifications where precise functional group control is required.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1g 10-20 days $40.90
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5g 10-20 days $191.14
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25g 10-20 days $916.97
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100g 10-20 days $3,033.73
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tert-Butyldiphenylsilane
Used as a silyl protecting group reagent in organic synthesis, particularly for alcohols and phenols. Its bulky structure provides high selectivity and stability under various reaction conditions, making it valuable in multi-step synthesis of complex molecules like pharmaceuticals and natural products. The tert-butyldiphenylsilyl (TBDPS) group offers strong resistance to hydrolysis and basic conditions, allowing selective deprotection in the presence of other silyl groups. Commonly employed in carbohydrate chemistry, nucleoside synthesis, and peptide modifications where precise functional group control is required.
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