1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid
≥95%
- Product Code: 148287
CAS:
1303972-81-7
| Molecular Weight: | 265.25 g./mol | Molecular Formula: | C₁₁H₁₇F₂NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18909780 | |
| Melting Point: | Boiling Point: | 356.4±42.0°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, dry seal |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders and metabolic diseases. Its structure allows for selective modification, making it valuable in medicinal chemistry for constructing drug candidates with improved metabolic stability and binding affinity. Commonly employed in the preparation of small-molecule inhibitors and receptor modulators where the difluorinated piperidine moiety enhances pharmacokinetic properties. Also utilized in solid-phase and solution-phase peptide-like synthesis due to the presence of the carboxylic acid and protected amine functional groups, enabling sequential coupling reactions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | £54.97 |
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| 0.250 | 10-20 days | £126.05 |
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| 1.000 | 10-20 days | £420.00 |
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| 5.000 | 10-20 days | £1,987.29 |
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1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders and metabolic diseases. Its structure allows for selective modification, making it valuable in medicinal chemistry for constructing drug candidates with improved metabolic stability and binding affinity. Commonly employed in the preparation of small-molecule inhibitors and receptor modulators where the difluorinated piperidine moiety enhances pharmacokinetic properties. Also utilized in solid-phase and solution-phase peptide-like synthesis due to the presence of the carboxylic acid and protected amine functional groups, enabling sequential coupling reactions.
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