cis-3-(Boc-amino)-5-(trifluormethyl)piperidine

97%

  • Product Code: 148372
  CAS:    1187055-62-4
Molecular Weight: 268.28 g./mol Molecular Formula: C₁₁H₁₉F₃N₂O₂
EC Number: MDL Number: MFCD22415260
Melting Point: Boiling Point: 307.3±42.0°C at 760 mmHg
Density: Storage Condition: 2-8°C, protected from light, stored in inert gas
Product Description: Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its piperidine backbone with defined stereochemistry makes it valuable for constructing selective receptor modulators. The Boc-protected amine allows for controlled deprotection and further functionalization in multi-step syntheses. The electron-withdrawing trifluoromethyl group enhances metabolic stability and influences binding affinity, making this compound especially useful in the design of bioactive molecules such as serotonin or dopamine receptor ligands. Commonly employed in medicinal chemistry for optimizing pharmacokinetic properties and improving target selectivity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days Ft47,182.14
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-
0.250 10-20 days Ft82,279.76
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-
1.000 10-20 days Ft247,259.62
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cis-3-(Boc-amino)-5-(trifluormethyl)piperidine
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its piperidine backbone with defined stereochemistry makes it valuable for constructing selective receptor modulators. The Boc-protected amine allows for controlled deprotection and further functionalization in multi-step syntheses. The electron-withdrawing trifluoromethyl group enhances metabolic stability and influences binding affinity, making this compound especially useful in the design of bioactive molecules such as serotonin or dopamine receptor ligands. Commonly employed in medicinal chemistry for optimizing pharmacokinetic properties and improving target selectivity.
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