tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
97%
- Product Code: 148421
CAS:
1215071-17-2
| Molecular Weight: | 235.23 g./mol | Molecular Formula: | C₁₀H₁₅F₂NO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD16140378 | |
| Melting Point: | Boiling Point: | 274.7±40.0°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, stored in inert gas |
Product Description:
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure supports the creation of conformationally restricted analogs, enhancing metabolic stability and receptor selectivity. Commonly employed in medicinal chemistry for constructing fluorinated piperidine derivatives, which are valuable in improving pharmacokinetic properties such as membrane permeability and resistance to oxidative degradation. Also utilized in the preparation of enzyme inhibitors and receptor modulators where fluorination plays a key role in potency enhancement.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White Powder |
| Purity (%) | 96.5-100 |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | €25.25 |
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| 5g | 10-20 days | €81.80 |
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| 10g | 10-20 days | €150.71 |
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| 25g | 10-20 days | €303.00 |
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| 50g | 10-20 days | €594.43 |
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| 100g | 10-20 days | €1,164.92 |
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tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure supports the creation of conformationally restricted analogs, enhancing metabolic stability and receptor selectivity. Commonly employed in medicinal chemistry for constructing fluorinated piperidine derivatives, which are valuable in improving pharmacokinetic properties such as membrane permeability and resistance to oxidative degradation. Also utilized in the preparation of enzyme inhibitors and receptor modulators where fluorination plays a key role in potency enhancement.
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