7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine

97%

  • Product Code: 148423
  CAS:    95897-49-7
Molecular Weight: 216.03 g./mol Molecular Formula: C₇H₆BrNO₂
EC Number: MDL Number: MFCD15530247
Melting Point: Boiling Point: 272.5°C at 760 mmHg
Density: Storage Condition: Room temperature, dry seal
Product Description: Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds. Its structure supports functionalization at multiple sites, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki and Buchwald-Hartwig aminations to build biaryl or arylamine linkages found in bioactive molecules. Also utilized in the preparation of selective serotonin reuptake inhibitors (SSRIs) and related antidepressant candidates. Its stability and reactivity profile make it suitable for late-stage derivatization in drug discovery programs.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $455.22
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250mg 10-20 days $555.38
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1g 10-20 days $1,482.77
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7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds. Its structure supports functionalization at multiple sites, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki and Buchwald-Hartwig aminations to build biaryl or arylamine linkages found in bioactive molecules. Also utilized in the preparation of selective serotonin reuptake inhibitors (SSRIs) and related antidepressant candidates. Its stability and reactivity profile make it suitable for late-stage derivatization in drug discovery programs.
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