1-([1,1'-biphenyl]-3-yl)-2,2-difluorocyclopropane-1-carboxylic acid
95%
- Product Code: 148859
| Molecular Weight: | 274.08 g./mol | Molecular Formula: | C₁₆H₁₂F₂O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and anti-inflammatory compounds. Its rigid biphenyl-cyclopropane scaffold enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and target engagement in central nervous system (CNS) therapies.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Yellow solid |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | €52.35 |
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| 0.500 | 10-20 days | €104.71 |
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| 1.000 | 10-20 days | €361.71 |
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| 5.000 | 10-20 days | €1,199.36 |
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1-([1,1'-biphenyl]-3-yl)-2,2-difluorocyclopropane-1-carboxylic acid
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and anti-inflammatory compounds. Its rigid biphenyl-cyclopropane scaffold enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and target engagement in central nervous system (CNS) therapies.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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