1-([1,1'-biphenyl]-2-yl)-2,2-difluorocyclopropane-1-carboxylic acid
95%
- Product Code: 148861
CAS:
2229448-80-8
| Molecular Weight: | 274.08 g./mol | Molecular Formula: | C₁₆H₁₂F₂O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its rigid biphenyl-cyclopropane structure enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and pharmacokinetic profiles.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White Solid |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $57.39 |
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| 0.500 | 10-20 days | $173.33 |
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| 1.000 | 10-20 days | $490.60 |
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| 5.000 | 10-20 days | $1,594.46 |
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1-([1,1'-biphenyl]-2-yl)-2,2-difluorocyclopropane-1-carboxylic acid
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its rigid biphenyl-cyclopropane structure enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and pharmacokinetic profiles.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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