5-bromo-3-iodo-1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridine
95%
- Product Code: 149673
CAS:
875639-15-9
Molecular Weight: | 477.12 g./mol | Molecular Formula: | C₁₄H₁₀BrIN₂O₂S |
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EC Number: | MDL Number: | MFCD11616451 | |
Melting Point: | Boiling Point: | 558.6ºC at 760 mmHg(lit.) | |
Density: | 2g/cm3 | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in Suzuki and Stille reactions to introduce aryl or vinyl groups, it helps optimize biological activity in drug candidates targeting tyrosine kinases. Also utilized in research settings for labeling and probing biological pathways due to the presence of halogen atoms that facilitate radiolabeling or fluorescence tagging.
Product Specification:
Test | Specification |
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Appearance | white to yellow to orange solid |
Purity (%) | 94.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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250mg | 10-20 days | ฿14,390.00 |
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5-bromo-3-iodo-1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridine
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in Suzuki and Stille reactions to introduce aryl or vinyl groups, it helps optimize biological activity in drug candidates targeting tyrosine kinases. Also utilized in research settings for labeling and probing biological pathways due to the presence of halogen atoms that facilitate radiolabeling or fluorescence tagging.
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