4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid
98%
- Product Code: 149694
CAS:
16506-27-7
| Molecular Weight: | 358.26 g./mol | Molecular Formula: | C₁₆H₂₁Cl₂N₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00866481 | |
| Melting Point: | Boiling Point: | 585.16 °C at 760 mmHg (lit.) | |
| Density: | 1.31 g/cm3 at 25 °C (lit.) | Storage Condition: | 2-8°C, dry |
Product Description:
Used as an intermediate in the synthesis of targeted cancer therapies, particularly in the development of antibody-drug conjugates (ADCs). Its structure allows for selective alkylation of DNA, making it valuable in creating cytotoxic agents that can be directed specifically to tumor cells. The carboxylic acid group enables conjugation to monoclonal antibodies via linker systems, facilitating controlled drug delivery. This compound is especially explored in treatments for hematological malignancies due to its potent mechanism of action and modifiable release profile.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | solid |
| Purity (%) | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | ฿5,340.00 |
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| 100mg | 10-20 days | ฿12,860.00 |
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| 250mg | 10-20 days | ฿26,730.00 |
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| bulk | 10-20 days | ฿0.00 |
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4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid
Used as an intermediate in the synthesis of targeted cancer therapies, particularly in the development of antibody-drug conjugates (ADCs). Its structure allows for selective alkylation of DNA, making it valuable in creating cytotoxic agents that can be directed specifically to tumor cells. The carboxylic acid group enables conjugation to monoclonal antibodies via linker systems, facilitating controlled drug delivery. This compound is especially explored in treatments for hematological malignancies due to its potent mechanism of action and modifiable release profile.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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