tert-Butyl (4R)-4-amino-3,3-difluoropiperidine-1-carboxylate

95%

  • Product Code: 150211
  CAS:    1820679-70-6
Molecular Weight: 236.26 g./mol Molecular Formula: C₁₀H₁₈F₂N₂O₂
EC Number: MDL Number: MFCD30386986
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed, and protected from light
Product Description: Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its protected amine and fluorinated piperidine structure make it valuable in medicinal chemistry for enhancing metabolic stability and improving binding selectivity. Commonly employed in the preparation of protease inhibitors and receptor modulators where stereochemistry and fluorination play critical roles in activity. The tert-butyl carbamate (Boc) group allows for easy deprotection under mild acidic conditions, enabling efficient incorporation into complex drug molecules during multi-step synthesis.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.050 10-20 days ฿11,890.00
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-
0.100 10-20 days ฿14,290.00
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-
0.250 10-20 days ฿22,900.00
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tert-Butyl (4R)-4-amino-3,3-difluoropiperidine-1-carboxylate
Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its protected amine and fluorinated piperidine structure make it valuable in medicinal chemistry for enhancing metabolic stability and improving binding selectivity. Commonly employed in the preparation of protease inhibitors and receptor modulators where stereochemistry and fluorination play critical roles in activity. The tert-butyl carbamate (Boc) group allows for easy deprotection under mild acidic conditions, enabling efficient incorporation into complex drug molecules during multi-step synthesis.
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