tert-Butyldiphenyl(prop-2-yn-1-yloxy)silane
95%
- Product Code: 150798
CAS:
88159-06-2
| Molecular Weight: | 294.47 g./mol | Molecular Formula: | C₁₉H₂₂OSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31555366 | |
| Melting Point: | 58-60 °C | Boiling Point: | 338.3±34.0 °C(Predicted) |
| Density: | 1.00±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C |
Product Description:
Used as a silyl protecting group in organic synthesis, particularly for terminal alkynes. It allows selective protection of the hydroxyl group in propargyl alcohol derivatives, enabling multi-step synthesis without interference from the alkyne functionality. The tert-butyldiphenylsilyl (TBDPS) group provides high stability under a variety of reaction conditions, including basic and mildly acidic environments, and can be removed selectively in the presence of other silyl groups. This makes it valuable in the synthesis of complex natural products, pharmaceuticals, and polyfunctional molecules where precise control over reactivity is required. Its bulky structure also helps reduce side reactions by steric shielding.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿10,300.00 |
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| 0.250 | 10-20 days | ฿18,720.00 |
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| 1.000 | 10-20 days | ฿37,440.00 |
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tert-Butyldiphenyl(prop-2-yn-1-yloxy)silane
Used as a silyl protecting group in organic synthesis, particularly for terminal alkynes. It allows selective protection of the hydroxyl group in propargyl alcohol derivatives, enabling multi-step synthesis without interference from the alkyne functionality. The tert-butyldiphenylsilyl (TBDPS) group provides high stability under a variety of reaction conditions, including basic and mildly acidic environments, and can be removed selectively in the presence of other silyl groups. This makes it valuable in the synthesis of complex natural products, pharmaceuticals, and polyfunctional molecules where precise control over reactivity is required. Its bulky structure also helps reduce side reactions by steric shielding.
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