3-(4-Bromo-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione
97%
- Product Code: 151434
CAS:
2093386-30-0
| Molecular Weight: | 337.17 g./mol | Molecular Formula: | C₁₄H₁₃BrN₂O₃ |
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| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The compound's bromo and isoindolinone groups facilitate conjugation with target-binding ligands, enhancing degradation of disease-related proteins. Also explored in medicinal chemistry for optimizing pharmacokinetic properties in small molecule therapeutics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | €119.57 |
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| 0.250 | 10-20 days | €202.74 |
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| 1.000 | 10-20 days | €592.27 |
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3-(4-Bromo-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The compound's bromo and isoindolinone groups facilitate conjugation with target-binding ligands, enhancing degradation of disease-related proteins. Also explored in medicinal chemistry for optimizing pharmacokinetic properties in small molecule therapeutics.
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