tert-Butyl 4-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
98%
- Product Code: 152045
CAS:
1446443-06-6
| Molecular Weight: | 344.21 g./mol | Molecular Formula: | C₁₈H₂₅BN₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22577263 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. The presence of the boronate ester group allows for efficient carbon-carbon bond formation under mild conditions, enabling the construction of biaryl and heteroaryl frameworks. Its indazole core is valuable in drug discovery due to its role as a bioisostere for purine bases, contributing to the development of kinase inhibitors and other biologically active compounds. The tert-butyl carbamate (Boc) protecting group ensures stability during synthesis and can be easily removed when needed, making it ideal for multi-step synthetic routes.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿2,630.00 |
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| 0.250 | 10-20 days | ฿4,270.00 |
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| 1.000 | 10-20 days | ฿11,500.00 |
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| 5.000 | 10-20 days | ฿40,250.00 |
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tert-Butyl 4-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. The presence of the boronate ester group allows for efficient carbon-carbon bond formation under mild conditions, enabling the construction of biaryl and heteroaryl frameworks. Its indazole core is valuable in drug discovery due to its role as a bioisostere for purine bases, contributing to the development of kinase inhibitors and other biologically active compounds. The tert-butyl carbamate (Boc) protecting group ensures stability during synthesis and can be easily removed when needed, making it ideal for multi-step synthetic routes.
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