(3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)(tert-butyl)dimethylsilane
95%
- Product Code: 152291
CAS:
1218789-51-5
| Molecular Weight: | 413.23 g./mol | Molecular Formula: | C₁₈H₃₀BBrO₃Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD12546591 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. The boronate ester group enables formation of carbon-carbon bonds with aryl or vinyl halides, allowing construction of complex aromatic systems. The silyl ether group acts as a protected phenol, which can be deprotected under mild acidic or basic conditions to release the free phenol when needed. This dual functionality makes it valuable in multi-step synthesis of pharmaceuticals, agrochemicals, and functional materials where selective reactivity and protection strategies are required. Its stability and selective reactivity profile support use in late-stage functionalization and parallel synthesis in drug discovery.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿960.00 |
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| 0.250 | 10-20 days | ฿1,590.00 |
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| 1.000 | 10-20 days | ฿4,270.00 |
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| 5.000 | 10-20 days | ฿14,910.00 |
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(3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)(tert-butyl)dimethylsilane
Used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. The boronate ester group enables formation of carbon-carbon bonds with aryl or vinyl halides, allowing construction of complex aromatic systems. The silyl ether group acts as a protected phenol, which can be deprotected under mild acidic or basic conditions to release the free phenol when needed. This dual functionality makes it valuable in multi-step synthesis of pharmaceuticals, agrochemicals, and functional materials where selective reactivity and protection strategies are required. Its stability and selective reactivity profile support use in late-stage functionalization and parallel synthesis in drug discovery.
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